Dr. Evdokia Anagnostou

Dr. Evdokia Anagnostou is a child Neurologist and clinician scientist at Bloorview Research Institute. Dr. Anagnostou's research focuses on the psychopharmacology and neuroimaging of autism. Dr. Anagnostou is principlal or co-investigator on multiple clinical trials in autism and has had extensive funding in both pharmacology and neuroimaging. She also leads the Ontario Brain Institute funded POND grant that embeds a clinical trial network in biomarkers core for ASD, ADHD, ID and OCD. Her research at Holland Bloorview focuses on the development of clinical trials to test novel compounds for the treatment of autism and related disorders. In collaboration with imaging researchers at SickKids, she is also studying the developmental trajectory of abnormalities in the frontostriatal circuitry in autism, and exploring the mechanisms of treatment response and side effects generation using fMRI, MR spectroscopy and DTI techniques.

Selected Recent Publications:

Mak-Fan KM, Morris D, Vidal J, Anagnostou E, Roberts W, Taylor MJ. White matter and development in children with an autism spectrum disorder. Autism. 2012 Jun 14. [Epub ahead of print] PubMed PMID: 22700988.

Jiang YH, Yuen RK, Jin X, Wang M, Chen N, Wu X, Ju J, Mei J, Shi Y, He M, Wang G, Liang J, Wang Z, Cao D, Carter MT, Chrysler C, Drmic IE, Howe JL, Lau L, Marshall CR, Merico D, Nalpathamkalam T, Thiruvahindrapuram B, Thompson A, Uddin M, Walker S, Luo J, Anagnostou E, Zwaigenbaum L, Ring RH, Wang J, Lajonchere C, Wang J, Shih A, Szatmari P, Yang H, Dawson G, Li Y, Scherer SW. Detection of Clinically Relevant Genetic Variants in Autism Spectrum Disorder by Whole-Genome Sequencing. Am J Hum Genet. 2013 Jul. Epub ahead of print

Kushki A, Drumm E, Pla Mobarak M, Tanel N, Dupuis A, Chau T, Anagnostou E. Investigating the autonomic nervous system response to anxiety in children with autism spectrum disorders. PLoS One. 2013 Apr;8(4):e59730. epub ahead of print/PubMed PMID 23577072

Anagnostou E, Soorya L, Chaplin W, Bartz J, Halpern D, Wasserman S, Wang AT, Pepa L, Tanel N, Kushki A and Hollander E. Intranasal oxytocin versus placebo in the treatment of adults with autism spectrum disorders: a randomized controlled trial. Mol Autism. 2012 Dec 5;3(1):16. doi: 10.1186/2040-2392-3-16.

Mak-Fan KM, Morris D, Vidal J, Anagnostou E, Roberts W, Taylor MJ. White matter and development in children with an autism spectrum disorder. Autism. 2012 Jun 14. [Epub ahead of print] PubMed PMID: 22700988.

Sato D, Lionel AC, Leblond CS, Prasad A, Pinto D, Walker S, O'Connor I, Russell C, Drmic IE, Hamdan FF, Michaud JL, Endris V, Roeth R, Delorme R, Huguet G, Leboyer M, Rastam M, Gillberg C, Lathrop M, Stavropoulos DJ, Anagnostou E, Weksberg R, Fombonne E, Zwaigenbaum L, Fernandez BA, Roberts W, Rappold GA, Marshall CR, Bourgeron T, Szatmari P, Scherer SW. SHANK1 Deletions in Males with Autism Spectrum Disorder. Am J Hum Genet. 2012 May 4;90(5):879-87. Epub 2012 Apr 12. PubMed PMID: 22503632; PubMed Central PMCID: PMC3376495.

Hollander E, Soorya L, Chaplin W, Anagnostou E, Taylor BP, Ferretti CJ, Wasserman S, Swanson E, Settipani C. A double-blind placebo-controlled trial of fluoxetine for repetitive behaviors and global severity in adult autism spectrum disorders. Am J Psychiatry. 2012 Mar;169(3):292-9. Erratum in: Am J Psychiatry. 2012 May;169(5):540. PubMed PMID: 22193531.

Ameis SH, Fan J, Rockel C, Voineskos AN, Lobaugh NJ, Soorya L, Wang AT, Hollander E, Anagnostou E. Impaired structural connectivity of socio-emotional circuits in autism spectrum disorders: a diffusion tensor imaging study. PLoS One. 2011;6(11):e28044. Epub 2011 Nov 23. PubMed PMID: 22132206; PubMed Central PMCID: PMC3223195.

Girgis RR, Slifstein M, Xu X, Frankle WG, Anagnostou E, Wasserman S, Pepa L, Kolevzon A, Abi-Dargham A, Laruelle M, Hollander E. The 5-HT(2A) receptor and serotonin transporter in Asperger's disorder: A PET study with [¹¹C]MDL 100907 and [¹¹C]DASB. Psychiatry Res. 2011 Dec 30;194(3):230-4. Epub 2011 Nov 12. PubMed PMID: 22079057; PubMed Central PMCID: PMC3225493.

Anagnostou E, Hansen R. Medical treatment overview: traditional and novel psycho-pharmacological and complementary and alternative medications. Curr Opin Pediatr. 2011 Dec;23(6):621-7. Review. PubMed PMID: 22001766.

Anagnostou E, Chaplin W, Watner D, Silverman JM, Smith CJ, Zagursky K, Kryzak LA, Corwin TE, Feirsen N, Tanel N, Hollander E. Factor analysis of repetitive behaviors in Autism as measured by the Y-BOCS. J Neuropsychiatry Clin Neurosci. 2011 Summer;23(3):332-9. PubMed PMID: 21948895.

Scahill L, McCracken JT, Bearss K, Robinson F, Hollander E, King B, Bregman J, Sikich L, Dukes K, Sullivan L, Anagnostou E, Donnelly C, Kim YS, Ritz L, Hirtz D, Wagner A. Design and subject characteristics in the federally-funded citalopram trial in children with pervasive developmental disorders. J Autism Dev Disord. 2012 Mar;42(3):432-40. PubMed PMID: 21667200.

Anagnostou E, Taylor MJ. Review of neuroimaging in autism spectrum disorders: what have we learned and where we go from here. Mol Autism. 2011 Apr 18;2(1):4. PubMed PMID: 21501488; PubMed Central PMCID: PMC3102613.

Kushki A, Chau T, Anagnostou E. Handwriting difficulties in children with autism spectrum disorders: a scoping review. J Autism Dev Disord. 2011 Dec;41(12):1706-16. Erratum in: J Autism Dev Disord. 2011 Dec;41(12):1717. PubMed PMID: 21350917.

Bernardi S, Anagnostou E, Shen J, Kolevzon A, Buxbaum JD, Hollander E, Hof PR, Fan J. In vivo 1H-magnetic resonance spectroscopy study of the attentional networks in autism. Brain Res. 2011 Mar 22;1380:198-205. Epub 2010 Dec 23. PubMed PMID: 21185269; PubMed Central PMCID: PMC3073642.

[email protected]

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Dr. Anthony Bailey

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Dr. Armando Bertone

Dr. Armando Bertone, PhD, is an Assistant Professor in the School/Applied Child Psychology & Human Development Programs of the Department of Educational and Counselling Psychology at McGill University. He is also a Supervisor in the Integrated Program in Neuroscience at McGill, as well as a Research Scientist at the University of Montréal Mental Health Research Institute (Hôpital Rivière-des-Praries site). In 2009, he founded and currently directs The Perceptual Neuroscience Lab (PNLab) for Autism and Development, with sites at both McGill University and l’Hôpital Rivière-des-Prairies in Montréal, Canada. A trained psychophysicist and clinical neuropsychologist, Dr. Bertone is interested in characterizing the development of perceptual and related processes (- cognitive, motor, learning, attentional, multi-sensory, etc.) in both in typical children and in individuals with developmental conditions (- ASDs and fragile-x syndrome). He has introduced the concept and utility of using perceptual phenotypes for developing biologically-plausible neural hypotheses consistent with visuo-perceptual abilities that are specific to autism. His team and collaborators are presently using different experimental approaches to assess how such altered perception affects sensory-related cognition and behavior in autism.

Recent Publications:

Charbonneau G, Bertone A, Lassonde M, Nassim M, Lepore F, Mottron L, Collignon O (2013). Multi-level deficits in the multisensory processing of audio-visual emotions expression in Autism Spectrum Disorders. Neuropsychologia, 51, 1002-1010.

Collignon O, Charbonneau G, Nassim M, Peters F, Lassonde M, Mottron L, Lepore F, Bertone A (2013). Reduced multisensory facilitation in persons with autism. Cortex, 49, 1704-1710.

Bertone A (2013). Acuity. In F Volkmar (ed.). Encyclopedia of Autism Spectrum Disorders. Springer.

Greffou S, Bertone A, Hahler EM, Hanssens J-M, Mottron L, Faubert J (2012). Postural hypo-reactivity in autism is contingent on development and visual environment: a fully immersive virtual reality study. Journal of Autism and Developmental Disorders, 42, 961-970.

Kéïta L, Mottron L, Dawson M, Bertone A (2011). Atypical lateral connectivity : a neural basis for altered visuo-spatial processing in autism. Biological Psychiatry, 70, 806-811.

Perreault A, Gurnsey R, Dawson M, Mottron L, Bertone A (2011). Increased sensitivity to visual mirror symmetry in autism. PLoS ONE, 6, e19519.

Bertone A, Hanck J, Kogan CS, Chaudhuri A, Cornish KM (2010). Using perceptual signatures to define and dissociate neural etiology : autism and fragile x syndrome as model conditions. Journal of Autism and Developmental Disorders, 40, 1531-1540.

Kéïta L, Mottron L, Bertone A (2010). Far visual acuity is unremarkable in autism : do we need to focus on crowding? Autism Research, 3, 333-341.

Bertone A, Hanck J, Kogan CS, Chaudhuri A, Cornish KM (2010). Associating neural alterations and genotype in autism and fragile x syndrome: incorporating perceptual phenotypes in causal modeling. Journal of Autism and Developmental Disorders, 40, 1541-1548.

Bertone A, Mottron L, Jelenic P, Faubert J (2005). Enhanced and diminished visuo-spatial information processing in autism depends on stimulus complexity. Brain, 128, 2430-2441.

Bertone A, Mottron L, Jelenic P, Faubert J (2003). Motion perception in autism: a ‘complex’ issue. Journal of Cognitive Neuroscience, 15, 218-225.

Armando Bertone, PhD
Assistant Professor
School/Applied Child Psychology
Department of Educational and Counselling Psychology
McGill University
3700 McTavish Street
Montreal, Quebec H3A 1Y2

Telephone: 514.398.3448
Email: [email protected]
Website: www.pnlab.ca

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Dr. Jessica Brian

Jessica A. Brian received her PhD in Clinical Developmental Psychology from York University in 2000. She completed a year-long internship at the Princeton Child Development Institute (PCDI) in New Jersey, with an emphasis on Applied Behaviour Analysis in autism intervention. Dr. Brian’s research interests include basic attention and inhibition in autism and related disorders, as well as early identification and intervention. She is a Clinician-Investigator at the Bloorview Research Institute at Holland Bloorview Kids Rehab, and co-directed the Autism Research Unit at SickKids for over ten years. Dr. Brian has been heavily involved in a multi-site longitudinal research program examining the emergence of autism in infants and toddlers and is co-leading an early intervention project for toddlers showing the very earliest sign of ASD.

Selected References:

Brian, JA., & Bryson, SE: Disembedding performance and recognition memory in autism/PDD. Journal of Child Psychology and Psychiatry 1996: 37: pp 865-872.

Brian, J.A., Tipper, S.P., Weaver, B., & Bryson, S: Inhibitory mechanisms in autism: Typical selective inhibition of location versus facilitated perceptual processing. Journal of Child Psychology and Psychiatry 2003: 44(4): pp 552-560.

Brian, JA, Landry R, Szatmari P, Niccols A, Bryson SE: Habituation in high-risk infants: Reliability and patterns of responding. Infant and Child Development 2003: 12: pp 387-394.

Cauley K, Brian JA: Teaching play-related verbalizations to children with autism using precision teaching. Journal of Precision Teaching and Celeration 2004: 19(2): pp 39-42.

Mitchell S, Brian J, Zwaigenbaum L, Roberts W, Szatmari P, Smith I, Bryson S: Early language and communication development of infants later diagnosed with autism spectrum disorder. Journal of Developmental & Behavioral Pediatrics 2006: 27(2) Supplement 2: pp S69-S78.

Bryson SE, Zwaigenbaum L, Brian JA, Roberts W, Szatmari P, Rombough V, McDermott C: A prospective case series of high-risk infants who developed autism. Journal of Autism and Developmental Disorders 2007: 37(1): pp 12-24.

Bryson SE, McDermott C, Rombough V, Brian J, Zwaigenbaum L: The Autism Observation Scale for Infants (AOSI): Scale development and reliability data. Journal of Autism and Developmental Disorders 2008: 38:731-738.

Brian JA, Bryson SE, Garon N, Roberts W, Smith I, Szatmari P, Zwaigenbaum L: Clinical assessment of autism in high-risk 18 month olds. Autism 2008: 12(5): 433-456.

[email protected]

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Dr. Melanie Couture

Melanie Couture is an Assistant Professor at Laval University in the Department of Rehabilitation of the Faculty of Medicine in Quebec City and a researcher at the Research Centre of the Centre hospitalier universitaire affilié de l’Hôtel Dieu de Lévis. She graduated from the ART program as a post-doctoral fellow from McGill University. Her research interests focus on neurodevelopmental assessment and developmental trajectory. She is a strong believer in clinical research and very sensitized to the importance of early identification of children with developmental disabilities. Melanie’s research in autism focuses on sensory-motor difficulties and how they may have an impact on the children’s daily activities and functional independence.

Melanie completed a B.Sc. in Occupational Therapy from University of Montreal, a Master in Child Study from Concordia University, and a Ph.D. in biomedical sciences (rehabilitation) at the University of Montreal. Throughout her graduate studies she also worked as an occupational therapist at the specialized home care services of Ste-Justine Hospital and in private practices.
Jasmin,, E., Couture M., McKinley,  P., Reid, G., Fombonne,  E., Gisel,  E. (2009). motor and daily living skills of preschool children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 39, 2, 231-241.
Fombonne, E. Couture, M., Gisel, E., Reid, G., Smith, I. FQRSC (2008-AC-121463) : Longitudinal study of the impact of sensory-motor skills on functional independence in activities of daily living of children with autism spectrum disorders. 47 300$. 2007-2009.

Mélanie Couture Ph.D. erg.
Professeure adjointe
École de réadaptation
Faculté de médecine et des sciences de la santé
Chercheure régulière au Centre de recherche clinique Étienne-LeBel du CHUS
Axe mère-Enfant
Université de Sherbrooke
3001, 12e avenue Nord
Sherbrooke (Québec) Canada J1H 5N4

Phone : (819) 820-6868 poste 12936
Fax : (819) 820-6864
[email protected]

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Dr. Mayada Elsabbagh

Mayada Elsabbagh, Ph.D. is Assistant Professor in Psychiatry at McGill University. Her research, in the area of early infancy and developmental disorders, is focused on understanding the brain basis of behavioural genetic disorders. Prior to returning to Canada from the UK in 2011, Mayada supported the successful launch of collaborative research networks in autism including BASIS and ESSEA, aimed at accelerating the pace of discovery in early autism. Mayada is active in the area of knowledge translation locally and internationally. She currently manages the Knowledge Translation portfolio for NeuroDevNet, a Canadian national Network of Center’s of Excellence. She was the recipient of the 2010 UK Economic and Social Research Council Neville Butler Memorial Prize for Longitudinal Research awarded in recognition of the public value and social relevance of her research.

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Dr. Shannon Johnson

Shannon Johnson is Associate Professor of Psychology and Director of the Clinical and Cognitive Neuropsychology Laboratory at Dalhousie University. She holds cross-appointments in the Departments of Pediatrics and Psychiatry and is a Scientific Staff member at the IWK Health Centre. Dr. Johnson received her Ph.D. in Clinical Neuropsychology from the University of Victoria. She completed her clinical internship at the Medical University of South Carolina and a post-doctoral fellowship in the Clinical and Cognitive Neuroscience Laboratory at Indiana University. Dr. Johnson’s research focuses on understanding differences in perception, cognition, and social-cognition in individuals with an autism spectrum diagnosis. She has a particular interest in clinical topics that are pertinent to adolescents and adults with ASD. Research topics in her lab span several areas of psychology including clinical psychology, health psychology, neuropsychology, cognitive psychology, and neuroscience. She also has experience with neurodegenerative and other neurodevelopmental disorders. Her teaching at Dalhousie focuses on child psychopathology and child assessment. Dr. Johnson is part of the ART Program Advisory Committee since 2011.

Recent publications

Bandstra, N.F., Johnson, S.A., Filliter, J.H. & Chambers, C.T. (in press). Self- and parent-reported pain for common painful events in children and adolescents with autism spectrum disorders. Clinical Journal of Pain.

Goodman, L., Phelan, H.L.. Johnson, S.A. (2012). Sex differences for the recognition of direct versus averted gaze faces. Memory, 20, 199-209.

Phelan, H.L., Filliter, J.H., & Johnson, S.A. (2011). Memory performance on the California Verbal Learning Test – Children’s Version in autism spectrum disorder. Journal of Autism and Developmental Disorders, 41, 518-523

Johnson, S.A., Blaha, L.M., Houpt, J.W., & Townsend, J.T. (2010). Systems Factorial Technology provides new insights on global-local information processing in autism spectrum disorders. Journal of Mathematical Psychology. 54, 53-72.

Johnson, S.A., Filliter, J.H., & Murphy, R.R. (2009). Discrepancies between self and parent perceptions of autistic traits and empathy in high functioning children and adolescents on the autism spectrum. Journal of Autism and Developmental Disorders, 39 (12), 1706 - 1715.

Contact Info
Shannon Johnson, Ph.D. (Registered Psychologist)
Assistant Professor
Department of Psychology
Dalhousie University
1355 Oxford Street
Halifax, Nova Scotia B3H 4J1
office: 902-494-4504
[email protected]

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Dr. Elizabeth Kelley

Dr. Beth Kelley grew up in Toronto and first became interested in individuals with autism while doing some volunteer work in the preschool at Surrey Place. She completed her undergraduate degree in Psychology at York University in 2000, and received her PhD in Developmental Psychology from the University of Connecticut in 2006, whereupon she accepted a position in the Psychology Department at Queen's University.  Dr. Kelley has published in a number of prestigious journals including "Child Development", "Current Directions in Psychological Science" and the "Journal of Autism and Developmental Disorders". She is funded by the National Institutes of Health, Canadian Foundation for Innovation, and Autism Speaks. 
Her research interests vary widely yet are all related to the idea that social difficulties are the core feature of ASD.  She currently is conducting projects in the following diverse areas:

Publications:

Li, A. S. M., Kelley, E., Evans, A., & Lee, K. (in press).  Exploring the ability to deceive in children with autism spectrum disorders. Journal of Autism and Developmental Disorders. DOI 10.1007/s10803-010-1045-4

 Brown, H., Ouellette-Kuntz, H., Hunter, D., & Kelley, E. (2010). Assessing need in school-aged children with an autism spectrum disorder. Research in Autism Spectrum Disorders, 4, 539-547. doi:10.1016/j.rasd.2009.12.009
 
Kelley, E., Naigles, L., & Fein, D. (2010). An in-depth examination of optimal outcome children with a history of autism spectrum disorders. Research in Autism Spectrum Disorders, 4, 526-538.  doi:10.1016/j.rasd.2009.12.001

Helt, M., Kelley, E., Kinsbourne, M. Pandey, J., Boorstein, H., Herbert, M., & Fein, D. (2008).  Can children with autism recover?  If so, how? Neuropsychology Reviews,18, 339-366.
 
Kamio, Y., Kelley, E., Robins, D., Swainson, B., & Fein, D (2007). Atypical    lexical/semantic processing in high-functioning pervasive developmental disorders without early language delay.  Journal of Autism and Developmental Disorders, 37, 1116-1122.

Swensen, L., Kelley, E., Fein, D., & Naigles, L. (2007). Children with autism display typical language learning characteristics: Evidence from preferential looking. Child Development, 78, 542-557.
 
Kelley, E., Paul, J., Fein, D., & Naigles, L. R. (2006). Residual language deficits in optimal outcome children with a history of autism.  Journal of Autism andDevelopmental Disorders, 36, 807-828.

Elizabeth Kelley, PhD
Assistant Professor
Department of Psychology
Queen's University
62 Arch St., H351
Kingston, ON K7L 3N6 CANADA
Phone: 613-533-2491
Fax: 613-533-2499
http://psyc.queensu.ca/asdstudies/index.html

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Dr. Tara Kennedy

Tara Kennedy, MD, PhD, FRCPC, is a Developmental Paediatrician who works with children and families affected by autism in her position as Clinical Leader of Paediatric Autism Rehabilitation Services at the Stan Cassidy Centre for Rehabilitation in Fredericton, New Brunswick. She is an Assistant Professor of Paediatrics at Dalhousie University. Dr. Kennedy received her paediatric training at Dalhousie University and her Developmental Paediatrics Fellowship training at the University of Toronto. She is actively involved in advocacy at the community level, and in the development and delivery of educational programs in the field of Child Development for medical trainees, physicians, and other health care professionals across North America. Dr. Kennedy’s academic interests are in the domain of Medical Education. She has a Master’s of Education degree from the Ontario Institute for Studies in Education, and a PhD in Medical Education from the Institute of Medical Science and the Wilson Centre, Faculty of Medicine, University of Toronto. Her research employs qualitative research methodology to explore issues related to independence in clinical training and supervision of clinical trainees. Other areas of research interest include knowledge translation, patient safety, and professional socialization.

Selected publications:

Kennedy, TJT, Regehr, G, Baker, GR, and Lingard, L. “Not unless it seems urgent”: A grounded theory study of credibility preservation during medical trainee requests for clinical support. BMJ, 2009, 338:b128.

Kennedy, TJT, Regehr, G, Baker, GR, and Lingard, L. Point of care assessment of trainee competence for independent clinical work. Academic Medicine, 2008, 83(10 suppl): S89-92.

Kennedy, TJT, Lingard, L, Baker, GR, Kitchen, L, and Regehr, G. Clinical oversight: Conceptualizing the relationship between supervision and safety. Journal of General Internal Medicine, 2007, 22(8): 1080-85.

Kennedy, TJT, and Lingard, L. Making sense of Grounded Theory. Medical Education, 2006, 40: 101–108.

Kennedy, TJT, Regehr, G, Rosenfield, J, Roberts, W, and Lingard, L. Exploring the gap between knowledge and behaviour: A qualitative study of clinician action following an educational intervention.  Academic Medicine, 2004, 79: 386-393.

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Dr. Gina Muckle

Gina Muckle, Ph.D. is a Full Professor of Developmental Psychology at Laval University. Researcher at the CHU de Québec Research Center in Québec City, she was also a Member of the Advisory Board for the Institute of Human Development, Child and Youth Health (IHDCYH) and Member of the Challenge Advisory Panel for Chemical Substances. Her area of expertise is behavioural and developmental teratology integrating epidemiological and toxicological based concepts. Her research is focused on the health, behaviour and development of infants and children. She is interested in the effects of prenatal exposure to teratogenic substances, such as tobacco, alcohol and environmental contaminants (mercury, lead, etc.). She is also interested in the determinants of the development of Inuit children, determinants such as anemia, familial violence and maternal distress. Her work has been funded by NIH, CIHR, FRSQ, Indian and Northern Affairs Canada and Health Canada.

Recent publications  (since 2011):
(*Corresponding author; + PhD student; post-doctoral researcher or research personnel under supervision)

+Desrosiers, C., +Boucher, O., +Forget-Dubois, N., Dewailly, E., Ayotte, P., Jacobson, S.W., Jacobson, J.L., *Muckle, G. (2013). Associations Between Prenatal Cigarette Smoke Exposure and Externalized Behaviors at School Age Among Inuit Children Exposed to Environmental Contaminants, Neurotoxicology and Teratology. doi: 10.1016/j.ntt.2013.07.010

Arbuckle, T., Fraser, W.D., Fisher, M. et al. (2013). Cohort profile : The maternal-Infant research on environmental Chemicals Research Platform. Paediatric and Perinatal Epidemiology, 27:415-425. doi: 10.111/ppe.12061

Dion, L.-A., Muckle, G., Bastien, C., Jacobson, S.W., Jacobson, J.L., Saint-Amour, D. (2013). Sex differences in visual evoked potentials in school-age children: What is the evidence beyond the checkerboard? International Journal of Psychophysiology. doi: 10.1016/j.ijpsycho.2013.03.001

+Dallaire, R., Dewailly, É., Ayotte, P., +Forget-Dubois, N., Jacobson, S.W., Jacobson J.L.,*Muckle, G. (2013). Effects of exposure to persistent organic pollutants and mercury through fish and marine mammal consumption on growth and gestation of Inuit newborns. Environmental International, 54: 85-91. doi: 10.1016/j.envint.2013.01.013

+Boucher, O., +Simard, M.-N., *Muckle, G., Rouget, F., Kadhel, P., Bataille, H., Chajès, V.,+Dallaire, R., Monfort, C., Thomé, J.-P., Multigner, L., & Cordier, S. (2013). Exposure to an organochlorine pesticide (chlordecone) and development of 18-month-old infants.NeuroToxicology, 35: 162-168.

+Pelé, F., Muckle, G., Costet, N., Garlantézec, R., Monfort, C., Multigner, L., Rouget, F., Cordier, S. (2013). Occupational solvent exposure during pregnancy and child behaviour at age2. Occupational Environmental Medicine, 70(2): 114-119. [PMID: 23112267].

Verner, M.A., Sonneborn, D., Lancz, K., Muckle, G., Ayotte, P., Dewailly, E., Kocan, A., Palkovičová, L., Trnovec, T., Haddad, S., Hertz-Picciotto, I., Eggesbø, M. (2013). Toxicokinetic Modeling of Persistent Organic Pollutant Levels in Blood from Birth to 45 Months of Age in Longitudinal Birth Cohort Studies. Environmental Health Perspectives, 121(1): 131-7. [PMID: 23086694].

Galloway, T., Niclasen, B.V.L., Muckle, G., Young, K., Egeland, G.M. (2012). Growth measures among preschool-age Inuit children living in Canada and Greenland. Scandinavian Journal of Public Health, 29. [PMID: 23108476].

Saint-Amour, D., Ethier, A. A., Boucher, O., Plusquellec, P., Bastien, C.H., Dewailly, E., Ayotte, P., Jacobson, S.W., Jacobson, J.L. Muckle, G. (2012). Contribution des neurosciences cognitives pour l'étude de l'impact des contaminants environnementaux sur le développement des fonctions cérébrales. Revue de Neuropsychologie, 4(3) : 163-173.

+Boucher, O., Jacobson, S.W., Plusquellec, P., Dewailly, E., Ayotte, P., +Forget-Dubois, N., Jacobson, J.L., & Muckle, G.* (2012). Prenatal methylmercury and postnatal lead exposure: risk factors for attention deficit hyperactivity disorder among Inuit children in Arctic Quebec. Environmental Health Perspectives, 120(10), 1456-1461.

Couture, A., Lévesque, B., Dewailly, É., Muckle, G., Déry, S., J.F. Proulx (2012). Lead exposure in Nunavik : From research to action. International Journal of Circumpolar Health, 71: 18591. [PMID: 22818717].

+Dallaire, R., Muckle, G.*, Rouget, F., Seurin, S., Monfort, C., Multigner, L., Bataille, H., Kadhel, P., Thomé, J.P., Jacobson, S. W., Boucher, O., Cordier, S. (2012). Cognitive, visual and motor development of infants exposed to chlordecone in Guadeloupe. Environmental Research, 118: 79-85.

+Boucher, O., Burden, M. J., Muckle, G., Saint-Amour, D., Ayotte, P., Dewailly, E., Nelson, C. A., Jacobson, S. W., and Jacobson, J. L. (2012). Response inhibition and error monitoring during a visual Go/No-go task in Inuit children exposed to lead, polychlorinated biphenyls, and methylmercury. Environmental Health Perspectives, 120: 608-615.

Valera, B., Muckle, B., Poirier, P., Jacobson, S.W., Jacobson, J.L., Dewailly, É. (2012). Cardiac autonomic activity and blood pressure among Inuit children exposed to mercury. Neurotoxicology, 33: 1067-1074.

Ethier, A.A., Muckle, G., Bastien, C., Dewailly, E., Ayotte, P., Arfken, C., Jacobson, S.W., Jacobson, J.L., Saint-Amour, D. (2012). Effects of environmental contaminant exposure on visual brain development: A prospective electrophysiological study in school-aged children. Neurotoxicology, 33(5):1075-85. [PMID: 22683800].

+Fraser, S.L, Muckle, G.*, Abdous, B.B., Jacobson, J.L., Jacobson, S.W. (2012) Effects of binge drinking on infant growth and development in an Inuit sample. Alcohol, 46(3):277-83.

*Muckle, G., +Laflamme, D., +Gagnon, J., +Boucher, O., Jacobson, J.L. and S. W. Jacobson (2011). Alcohol, Smoking, and Drug use among Inuit women of childbearing age during pregnancy and the risk to children. Alcoholism : Clinical and experimental research. 35(6): 1081-1091.

+Boucher, O., Burden, M.J., Muckle, G., Saint-Amour, D., Ayotte, P., Dewailly, É., Nelson, C.A., Jacobson, S.W., & Jacobson, J.L. (2011). Neurophysiologic and neurobehavioral evidence of beneficial effects of prenatal omega-3 fatty acid intake on memory function at school age. The American Journal of Clinical Nutrition, 03, 1025-1037.

Ouellet-Morin, I., Dionne, G., Lupien, S.J., Muckle, G., Côté, S., Pérusse, D., Tremblay, R.E., Boivin, M. (2011). Prenatal alcohol exposure and cortisol activity in 19-month-old toddlers: An investigation of the moderating effects of sex and testosterone. Psychopharmacology. 214:297- 307

Jacques, C., Levy, É., Muckle, G., Jacobson, S.W., Bastien, C.H., Dewailly, É., Ayotte, J.L., Saint-Amour, D. (2011). Long-term Effects of Prenatal Omega-3 Fatty Acid Intake on Visual Function in School-Age Children. The Journal of Pediatrics. 158(1) 83-90.

Gina Muckle, Ph.D.
Professor
École de psychologie,
Pavillon Félix-Antoine Savard
2325, rue des Bibliothèques
Université Laval, Québec (QC), G1V 0A6
Tel. : 418-656-2131 poste 4680
Fax : 418-656-3646
E-mail : [email protected]

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Dr. David Nicholas

Dr. David Nicholas is Associate Professor in the Faculty of Social Work, University of Calgary, and is cross appointed as a Senior Associate Scientist, Research Institute at The Hospital for Sick Children, Toronto. He brings a strong background in quality of life research with a focus on family experience related to childhood disability and chronic health conditions. Currently, he is evaluating two recently developed, innovative online social support interventions for youth and parents respectively. He is principal investigator in current studies examining both mothers’ and fathers’ caregiving roles and experiences related to autism as well as co-leading a systematic review of interventions for children and adults with autism. He is currently completing a book examining family-centred care as it relates to inter-professional practice. This examination addresses means for understanding and supporting the role of family members, in the context of inter-professional teams, as they facilitate and support service delivery plans for young persons with chronic conditions. Dr. Nicholas holds funding from the Canadian Institutes for Health Research and the Social Sciences and Humanities Research Council of Canada. He brings leadership in the examination of psychosocial adaptation to childhood chronic illness and disability, and has a particular interest and background in knowledge translation.

Interests: Quality of life, social support, parenting, the use of advanced technology in fostering support, and knowledge translation and mobilization.

Associate Professor
Location: Edmonton
Telephone: 780.492.8094
Email: [email protected]
Degrees: PhD

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Aparna Nadig

Aparna Nadig attained a PhD in Cognitive Science and then moved into autism research via postdoctoral training with Dr. Sally Ozonoff at the UC Davis MIND Institute. She is currently Associate Professor in the School of Communication Sciences and Disorders at McGill University in Montreal. She is the director of the PoP Lab, whose research focuses on pragmatic development, social communication, and language and communication in individuals with autism spectrum disorders. This research has spanned development from infants at risk for autism to transition support programs for adults with ASD.

Publications:

Nadig, A., & Shaw, H. (FirstView 2012). Acoustic marking of prominence: How do preadolescent speakers with and without high-functioning autism mark contrast in an interactive task? Language and Cognitive Processes.

Bang, J., Burns, J. & Nadig, A. (FirstView 2012). Conveying subjectivity in conversation: Mental state terms and personal narratives in typical development and children with high functioning autism. Journal of Autism and Developmental Disorders.

Bani Hani, H., Gonzalez-Barrero, A. & Nadig, A. (FirstView, Oct 2012). Children's referential understanding of novel words and parent labelling behaviours: similarities across children with and without autism spectrum disorders. Journal of Child Language, 1-32.

Bourguignon, N., Nadig, A. & Valois, D. (2012). The Biolinguistics of Autism: Emergent Perspectives. Biolinguistics, 6 (2), 124-165.

Nadig, A. & Shaw, H. (2011). Expressive prosody in high-functioning autism: Increased pitch range and what it means to listeners. Journal of Autism and Developmental Disorders, 42 (4), 499-511.

Vivanti, G., McCormick, C., Young, G., Abucayan, F., Hatt., N., Nadig, A., Ozonoff, S. and Rogers, S. (2011). Intact and impaired mechanisms of action understanding in autism. Developmental Psychology, 47 (3), 841-856.

Nadig, A., Lee, I., Singh, L., Bosshart, K. & Ozonoff, S. (2010). How does the topic of conversation affect verbal exchange and eye gaze? A comparison between typical development and high-functioning autism. Neuropsychologia, 48 (9), 2730-2739.

Nadig, A., Vivanti, G. & Ozonoff, S. (2009). Object descriptions under different communicative demands: How do children with and without autism adapt? Autism Research, 2, 1-14.

Aparna Nadig, Ph.D.
Associate Professor, McGill University
School of Communication Sciences and Disorders
1266 Pine Avenue West
Montreal, QC H3G 1A8

Phone: 514.398.4141
Fax: 514.398.8123
[email protected]
Lab Website -- http://poplab.mcgill.ca/index.html

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Dr. Rob Nicolson

Dr. Nicolson attended medical school at The University of Western Ontario and completed his residency in Psychiatry at the University of Toronto. Following the completion of his residency in Psychiatry at The University of Toronto, he worked as a visiting scientist in the Child Psychiatry Branch of the National Institute of Mental Health in Bethesda, Maryland. Dr. Nicolson is an Associate Professor in the Departments of Psychiatry, Psychology, and Medical Biophysics at The University of Western Ontario. He is also Chair of the Division of Developmental Disabilities and co-director of the Autism Research Program at Western. Dr. Nicolson’s research focuses on brain imaging in autism using a variety of imaging modalities.

Selected publications:

Brun CC, Nicolson R, Leporé N, Chou YY, Vidal CN, Devito TJ, Drost DJ, Williamson PC, Rajakumar N, Toga AW, Thompson PM. Mapping brain abnormalities in boys with autism. Human Brain Mapping 2009;30:3887-3900.

Vidal CN, Nicolson R, DeVito T, Hayashi KM, Gaega J, Drost DJ, Williamson PC, Rajakumar N, Toga AW, Thompson PM. Three-dimensional mapping of the lateral ventricles in autism. Psychiatry Research: Neuroimaging 2008;163:106-115.

DeVito TJ, Drost DJ, Neufeld RWJ, Rajakumar N, Pavlosky W, Williamson PC, Nicolson R. Evidence for cortical dysfunction in autism: a proton magnetic resonance spectroscopic imaging study. Biological Psychiatry 2007;61:465-473.

Nicolson R, DeVito TJ, Vidal CN, Sui Y, Hayashi KM, Drost DJ, Williamson PC, Nagalingam R, Toga AW, Thompson PM.  Detection and mapping of hippocampal abnormalities in autism. Psychiatry Research: Neuroimaging 2006;148:11-21.

Vidal CN, Nicolson R, DeVito T, Hayashi KM, Gaega J, Drost DJ, Williamson PC, Rajakumar N, Sui Y, Dutton RA, Toga AW, Thompson PM.  Mapping corpus callosum deficits in autism: an index of aberrant cortical connectivity. Biological Psychiatry 2006;60:218-225.

Hendry J, DeVito T, Gelman N, Rajakumar N, Williamson PC, Drost D, Nicolson R. Tissue abnormalities in autism detected through transverse relaxation time imaging. NeuroImage 2006;29:1049-1057.

Nicolson R, Craven-Thuss B, Smith J. A prospective, open-label trial of galantamine in autistic disorder. Journal of Child and Adolescent Psychopharmacology 2006;16:621-629.

Rob Nicolson
Department of Psychiatry,
The University of Western Ontario
800 Commissioners Road East,
B8-026,
London, Ontario.
N6A-5W9.

Phone: (519) 685-8427
Fax: (519) 685-8595
Email: [email protected]

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Dr. Veronica Smith

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Dr. Jim Tanaka

Dr. Jim Tanaka is a professor of psychology from the University of Victoria, British Columbia and director of the Centre for Autism Research Technology and Education (CARTE). His research focuses on the role that perceptual experience plays in shaping the cognitive and brain mechanisms of human object and face recognition. Using psychophysical methods and event-related potentials, Jim studies the face processes of healthy adults and adults who have suffered brain damage. He also examines the development of face recognition in typically developing children as well as its dysfunction and rehabilitation in children with clinical disorders. With colleagues at the Yale Child Study Centre, Dr. Tanaka authored the Let's Face It!software, a program designed to improve the face processing skills of children with autism. Jim is the associate editor for the journal Visual Cognition.

Tanaka, J.W. and Pierce, L.J. (2009). The neural plasticity of other-race face recognition. Cognitive, Affective and Behavioral Neuroscience, 9, 122-131.

Wolf., J.M., Tanaka, J.W., Klaiman, C., Cockburn, J. Herlihy, L., Brown, C., South, M., McPartland, J., Kaiser, M. D., Phillips, R. and Schultz, R. T. (2008). Specific impairment of face processing abilities in children with autism spectrum disorder using the Let's Face It! Skills Battery, Autism Research, 1, 329-340.

Bukach, C.M., Le Grand, R., Kaiser, M., Bub, D. & Tanaka, J.W. (2008). Preservation of mouth region processing in two cases of prosopagnosia.  Journal of Neuropsychology,  2,  227-244.

Tanaka, J.W., Curran, T, Porterfield, A., & Collins (2006). The activation of pre-existing and acquired face representations: The N250 ERP as an index of face familiarity. Journal of Cognitive Neuroscience, 18, 1488-1497.

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Dr. Tracy Vaillancourt

Dr. Tracy Vaillancourt is a Canada Research Chair in Children’s Mental Health and Violence Prevention at the University of Ottawa where she is cross-appointed as a full professor in the Faculty of Education (counselling program) and in the School of Psychology, Faculty of Social Sciences. Dr. Vaillancourt is also an adjunct professor in the Department of Psychology, Neuroscience, & Behaviour at McMaster University and a core member of the Offord Centre for Child Studies. She received her B.A., M.A., and Ph.D. from the University of British Columbia (human development), her post-doctoral diploma from the University of Montreal and Laval University (developmental psychology), and post-doctoral re-specialization in applied child psychology (clinical) from McGill University. Dr. Vaillancourt’s research examines the links between aggression and children’s mental health functioning, with a particular focus on social neuroscience. She is currently funded by the Canadian Institutes for Health Research.

Publications

Vaillancourt, T ., deCatanzaro, D., Duku, E., Muir, C. ( 2009). Androgen dynamics in the context of children's peer relations: An examination of the links between testosterone and peer-victimization. Aggressive Behavior, 35, 103-113.

Miller, J., & Vaillancourt, T. & Boyle, M. (2009). Examining the heterotypic continuity of aggression using teacher reports: Results from a national Canadian study . Social Development, 18, 164-180.

Vaillancourt, T ., McDougall, P., Krygsman, A., Hymel, S., Miller, J., Stiver, K., & Davis, C. (2008). Bullying: Are researchers and children/youth talking about the same thing? International Journal of Behavioral Development, 32, 486-495.

Vaillancourt, T ., Duku, E, deCatanzaro, D., MacMillan, H., & Muir, C., & Schmidt, L.A. (2008). Variation in hypothalamic-pituitary-adrenal axis activity among bullied and non-bullied children. Aggressive Behavior, 34, 294-305.

Miller, J.L., Schmidt, L.A., & Vaillancourt, T. (2008). Shyness, Sociability, and Eating Problems in a Non-clinical Sample of Female Undergraduates. Eating Behaviors, 9, 352-359.

Pagani, L.S., Japel, C., Vaillancourt, T. , Tremblay, R.E. & Cote, S. (2008). Links Between Life Course Trajectories of Family Dysfunction and Anxiety During Middle Childhood. Journal of Abnormal Child Psychology, 36 , 41-53.

Boylan, K., Vaillancourt, T., Boyle, M., Szatmari, P. ( 2007 ). Comorbidity of internalizing disorders in children with oppositional defiant disorder. European Journal Child and Adolescent Psychiatry, 16(8), 484-494.

Vaillancourt, T ., Miller, J., Fagbemi, J, Cote, S., & Tremblay, R.E. (2007). What Predicts Early Indirect Aggression Trajectory Group Membership? A Nationally Representative Longitudinal Study of Canadian Children Aged 2 to 10. Aggressive Behavior , 33, 1-13.

Cote , S., Vaillancourt, T., Barker, T., Nagin, D., & Tremblay, R.E. (2007). The joint development of physical and indirect aggression: Predictors of continuity and change during childhood. Development and Psychopathology, 19, 37-55.

Miller, J. & Vaillancourt, T. (2007). The relation between childhood peer victimization and adult perfectionism: Are victims of indirect aggression more perfectionistic? Aggressive Behavior , 33, 1-12.

Maggi, S., Hertzman, C., & Vaillancourt, T. (2007). Changes in smoking behaviours from late childhood to adolescence. Health Psychology, 26, 232-240.

Research Interests

• Aggression (Psychology of education)

• Bullying in schools (Counselling)

• Mental health (children) (Psychology of education)

• Social neuroscience (Psychology of education)

Dr. Jonathan Weiss

Jonathan Weiss, Ph.D., is an Assistant Professor in the Department of Psychology at York University, and Clinical Psychologist, who works with children, adolescents, and adults with autism spectrum disorders. He completed a post-doctoral fellowship in the Dual Diagnosis Program at the Centre for Addiction and Mental Health, and was a research fellow in the Department of Psychiatry at the University of Toronto. His research focuses on the prevention and treatment of mental health problems in people with autism spectrum disorders and/or intellectual disabilities across the lifespan. He conducts studies into how people with developmental disabilities access mental health care in Ontario, and is interested in their health service needs, their emergency service use, and their experiences of psychiatric crisis. Families play a critical role in the health of people with developmental disabilities by providing them with care and enabling their access to health services, and he is currently focused on learning about the experience of family caregivers. He is interested in program development and evaluation, and in particular on the impact of Special Olympics on the psychological well-being of participants, and of cognitive-behavioural and social skill interventions to promote resilience and improve the mental health of children and adults with developmental disabilities. Dr. Weiss holds the CIHR Chair in Autism Spectrum Disorders Treatment and Care Research, as well as operating funds from the Canadian Institutes of Health Research and Social Sciences and Humanities Research Council. He also holds a New Investigator Fellowship from the Ontario Mental Health Foundation.

Representative Publications:

Weiss, J.A., & Lunsky, Y. (in press). The family distress scale: A measure of crisis in caregivers of individuals with autism spectrum disorders. Journal of Child and Family Studies. DOI: 10.1007/s10826-010-9419-y

Cappadocia, M. C., & Weiss, J. A. (in press). Review of social skills training groups for youth with Asperger Syndrome and High Functioning Autism. Research in Autism Spectrum Disorders.

Weiss, J. A., & Lunsky, Y. (2010). Group cognitive behaviour therapy for adults with Asperger syndrome and anxiety or mood disorder: A case series. Clinical Psychology & Psychotherapy, 17, 438-446.

Weiss, J. A., Lunsky, Y. & Morin, D. (2010). Psychology graduate student training in developmental disability: A Canadian survey. Canadian Psychology, 51(3), 177 – 184.

Weiss, J. A., Lunsky, Y., Gracey, C., Canrinus, M., & Morris, S. (2009). Emergency psychiatric services for individuals with intellectual disabilities: Caregivers’ perspectives. Journal of Applied Research in Intellectual Disabilities, 22(4), 354-362.

Contact Information:

Jonathan Weiss, Ph.D., C. Psych
Assistant Professor, Dept. of Psychology
York University
Behavioural Science Building
4700 Keele St.,
Toronto, ON, M3J 1P3
[email protected]
Tel: 416-736-2100 ext. 22987

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Dr. Rosanna Weksberg

Rosanna Weksberg, MD, PhD, is a Professor of Pediatrics and Medical Genetics at the Hospital for Sick Children and the University of Toronto.  She has over 100 publications in the areas of epigenetics, imprinting, growth control and neurodevelopment.  Over the last 10 years her research has also on elucidating the biological basis and environmental contributors to neurodevelopmental disorders such as early onset psychosis and autism. She also studies the effects of environmental exposures (assisted reproduction, therapeutic agents) on epigenotype. Dr. Weksberg is currently funded by CIHR and CFI.   She organized a Workshop on Genetic and Epigenetic Outcomes Following Assisted Reproductive Technology in Toronto in 2005.  She is a Founding Member of the Organization for the Study of Sex Differences and has been on the Organizing Committee for their Annual Conferences held in Washington, New Orleans and Toronto in 2007, 2008, and 2009 respectively. Dr. Weksberg is an Associate Editor for the American Journal of Medical Genetics and the Journal of Neurodevelopment. 

R. Weksberg, MD, PhD, FRCPC, FCCMG, FACMG
Clinical Geneticist, Division of Clinical & Metabolic Genetics
Senior Associate Scientist, Research Institute
Hospital for Sick Children
Professor of Paediatrics and Genetics
Institute of Medical Science
University of Toronto

Journals:

Guo L, Choufani S, Ferreira J, Chitayat D, Shuman C, Uxa R, Keating S, Kingdom J, Weksberg R. Altered gene expression and methylation of human chromosome 11 imprinted region in small for gestational age (SGA) placentae. Developmental Biology.2008: 320 (1); 79-91.

Marshall C, Noor A, Vincent J, Lionel A, Feuk L, Skaug J, Shago M, Moessner R, Pinto D, Ren Y, Thiruvahindrapduram B, Fiebig A, Schreiber S, Friedman J, Ketelaars CEJ, Vos YJ, Ficicioglu C, Kirkpatrick S, Nicholson R, Sloman L, Summers A, Gibbons C, Teebi A, Chitayat D, Weksberg R, Thompson A, Vardy C, Crosbie V, Luscombe S, Baatjes R, Zwaigenbaum L, Roberts W, Fernandez B, Szatmari P, Scherer S. Structural variation of chromosomes in Autism spectrum disorder. American Journal of Human Genetics. Am J Hum Genet. 2008: 82(2):477-88. Epub 2008 Jan 17

Konen O, Armstrong D, Clarke H, Padfield N, Weksberg R, Blaser S. C1-2 vertebral anomalies in 22q11.2 microdeletion syndrome. Pediatr Radiol. 2008: 38(7): 766-71.

Greer KJ, Kirkpatrick SJ, Weksberg R, Pauli RM. Beckwith-Wiedemann syndrome in adults: observations from one family and recommendations for care. Am J Med Genet A. 2008: 146A (13) 1707-12.

Buchanan J, Carson A, Chitayat D, Malkin D, Meyn S, Ray P, Shuman C, Weksberg R, Scherer S. The cycle of genome-directed medicine.  Genome Medicine. 2009; 1(1); 1-7.

Ortiz-Neira C, Traubici J, Epelman M,  Moineddin R, Shuman C, Weksberg R, Daneman A: Sonographic assessment of the renal growth of the kidneys of patients with Beckwith-Wiedemann syndrome: The Beckwith-Wiedemann syndrome renal nomogram.  Clinic. 2009 Feb; 64 (1):41-4.

Weksberg R, Shuman C, Beckwith B. Beckwith-Wiedemann syndrome. European Journal of Human Genetics. 2009; 18: 8-14.

Horike S, Ferreira J, Meguro-Horike M, Choufani S, Smith AC, Shuman C, Meschino W, Chitayat D, Zackai E, Scherer S, Weksberg R. Screening of DNA methylation at the H19 promoter or the distal region of its ICR1 ensures efficient detection of chromosome 11p15 epimutations in Russell-Silver syndrome. American Journal of Medical Genetics. 2009 Nov; 149A (11):2415-23.

Shuman C, Weksberg R. Beckwith-Wiedemann Syndrome in: GeneReviews at GeneTests: Medical genetics information resource [database online]. Copyright, University of Washington, Seattle, www.genetests.org. 2009.  In Press.

Books:

Weksberg R, Shuman C. Beckwith-Wiedemann syndrome and hemihypertrophy.  In:  Management of Genetic Syndromes (3rd ed. 2009) (Cassidy SB, Allanson JE, eds).  John Wiley & Sons, Inc, New York 2009. In Press.

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